Five people have sustained significant injuries following an explosion at a mine in central Queensland.

The five are all in a serious condition “with potentially significant burns”, and have been taken to Moranbah Hospital following the incident at the Grosvenor Coal Mine on Wednesday afternoon.

A Queensland Ambulance Service spokesperson said the five will be transported by air to another hospital.

“We have multiple aero-medical responses to assist to with the retrieval of those patients from Moranbah Hospital,” they said.

Queensland Fire Service and Emergency Services says they were not called to the mine.

Mine operator Anglo American has evacuated the worksite, all employees have been accounted for, and family members of those who have been injured have been contacted, the ABC reported.

Union safety inspectors attended the site and will investigate the causes of “what appears to be an ignition of gas on the longwall face”, the mining union said in a statement.

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CFMEU Queensland district president Stephen Smyth said the immediate priority was taking care of those injured.

“Explosions are the worst nightmare for underground coal miners,” he said.

Queensland Mines Minister Anthony Lynham said his thoughts and prayers are with the injured workers and operation at the site has ceased.

Dr Lynham said two mine inspectors are on site and two more are expected to arrive on Thursday.

“Worker safety is in this government’s DNA and I expect a thorough independent investigation by the mine safety regulator,” he said in a statement on Wednesday.

Anglo American has been contacted for comment.

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AAP