The murder of a Brisbane father in the front yard of his home does not appear to be a random attack, but police don't yet have a motive for the horrific crime.

The 35-year-old victim suffered fatal wounds, from a knife or similar weapon, after apparently being lured out of his home at Kuraby in Brisbane's south about 12.30am on Wednesday.

A manhunt for his attacker is underway, but police say there's nothing to suggest that the Muslim man was murdered on the basis of his race or religion.

But 

So far the murder weapon has not been found.

The man's wife and four children were inside the house when the man was killed, Detective Superintendent Tony Fleming told reporters on Wednesday.

"She's obviously distressed," he said of the man's wife.

Police who found the man had taken great care to shield the children from any glimpse of the victim's body, as they were removed from the home and handed over to relatives who'll care for them.

Det Fleming said the victim ran businesses in the local area, but there was nothing in his character that had raised concerns with police.

AAP